The University of Pittsburgh School of Medicine and UPMC (University of Pittsburgh Medical Center) invite applications and nominations for the position of director of the newly created Institute for Personalized Medicine. The University of Pittsburgh has emerged as a national research leader, ranked among the top 10 educational and research institutions in NIH funding. Within the School of Medicine, areas of research strength include structural biology; cell and molecular biology; drug discovery and design; vaccine development; organ transplantation/immunology; stem cell biology and tissue engineering; medical device development; cancer research and therapy; cardiology and cardiovascular biology; bioinformatics and computational/systems biology; psychiatry, neurobiology, systems neuroscience, and neurological surgery; reproductive and developmental biology; comparative effectiveness research; and clinical research/clinical trials. UPMC is an integrated global health enterprise and one of the nation's leading academic health care systems, with $9 billion in revenues for fiscal year 2011. UPMC has more than 500,000 employees; nearly 5,000 affiliated physicians; more than 20 hospitals as well as specialized outpatient facilities, cancer centers, imaging services, and international sites; and a health insurance plan. The mission of the University of Pittsburgh Institute for Personalized Medicine is to apply new knowledge in genetics, genomics, and other disciplines to advance evidence-based medicine, leading to improved models of disease prevention and treatment in individuals. As evidence-based practice decreases variation in population-based care for specific diseases, appropriate treatment variation then needs to be reintroduced on the basis of specific aberrant molecular pathways and manifestations of an individual's genes and environment in a temporal context. Our goal is to become a major leader in personalized medicine research and to apply this knowledge to yield improved outcomes and decreased costs. The University of Pittsburgh and UPMC hope to attract an international leader in the emerging and rapidly advancing field of personalized medicine. The ideal candidate will have a recognized reputation for innovative scholarship, a distinguished track record of research support and publications, and leadership experience. Candidates should be committed to creative, team-based translational research, the exemplary education of students and trainees, and continued faculty development. Candidates should qualify for the academic rank of professor with tenure. The University of Pittsburgh and UPMC have pledged significant resources to this important new imitative. The director of the Institute for Personalized Medicine will report to the University's senior vice chancellor for the health sciences and the president of UPMC.